Effect of urokinase on fibrinolysis and fibrinogenolysis.

نویسندگان

  • O Matsuo
  • Y Nishida
  • K Akazawa
  • H Mihara
چکیده

The thrombolytic (fibrinolytic) effect of the urinary plasminogen activator, urokinase (UK), was compared with its fibrinogenolytic effect, using an artificial circulating system, and in in vivo pulmonary embolus and femoral vein thrombosis models. The thrombus lysing efficiency (fibrinolysis/fibrinogenolysis) was, in all cases, below 1.00, indicating that fibrinogenolysis is a primary function of UK while fibrinolysis is a secondary one.

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عنوان ژورنال:
  • The Japanese journal of physiology

دوره 32 5  شماره 

صفحات  -

تاریخ انتشار 1982